BACKGROUND:Hairy/Enhancer of Split (Hes) proteins are targets of the Notch signaling pathway and make up a class of basic helix-loop-helix (bHLH) proteins that function to repress transcription. Data from Hes1 deficient mice suggested that Hes1. like Notch1. is necessary for the progression of early T cell progenitors. https://hwjmmqobl0z3k.tokka-blog.com/35183000/introducing-a-registry-of-indigenous-persons-in-russia-rationale-and-challenges