Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs). but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear. To address this question. we generated new mouse models with ablation of Col2+ cells at either the embryonic or postnatal stages. https://www.markymarkscott.com/product-category/cotton-fibers/